Vertex Pharmaceuticals Inc (VRTX)

Currency in USD
434.64
+1.10(+0.25%)
Real-time Data·
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Fair Value
Day's Range
433.39438.84
52 wk Range
362.50507.92
Key Statistics
Prev. Close
433.54
Open
437.07
Day's Range
433.39-438.84
52 wk Range
362.5-507.92
Volume
453.48K
Average Vol. (3m)
1.29M
1-Year Change
0.0899%
Book Value / Share
76.22
Fair Value
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Fair Value Upside
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VRTX Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
548.10
Upside
+26.11%
Members' Sentiments
Bearish
Bullish
ProTips
9 analysts have revised their earnings downwards for the upcoming period

Vertex Pharmaceuticals Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Buy
Technical Indicators
Strong Buy
Moving Averages
Buy

Analyst Ratings

27 Buy
5 Hold
1 Sell
Ratings:
33 analysts
Overall Consensus
Buy

Analysts 12-Month Price Target:

Average 548.10
(+26.11% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
JPMorgan
Buy515.00+18.49%-New CoverageMay 20, 2026
BMO Capital
Hold17.00-96.09%-MaintainMay 08, 2026
Barclays
Buy615.00+41.50%607.00MaintainMay 06, 2026
Cantor Fitzgerald
Buy590.00+35.75%590.00MaintainMay 05, 2026
Morgan Stanley
Buy616.00+41.73%612.00MaintainMay 05, 2026

Vertex Pharmaceuticals Inc SWOT Analysis


Competitive Dynamics
Vertex faces competition from VERA's atacicept, already at BLA stage, creating pressure to demonstrate superior efficacy and capture market share quickly
Market Opportunity
The kidney disease franchise targets a multi-billion-dollar market across IgAN and PMN indications, with potential for first-in-class designation
Analyst Perspectives
Average price target stands at $446, with ratings ranging from Equal Weight to Buy, reflecting divergent views on execution risk versus franchise potential
Kidney Drug Promise
Povetacicept achieved 64% reduction in key kidney disease markers through dual BAFF/APRIL blockade, surpassing single-pathway competitors
Read full SWOT analysis

Vertex Pharmaceuticals Inc Earnings Call Summary for Q1/2026

  • Q1 2026 EPS of $4.47 beat estimates by 3.23%, though revenue of $2.99B missed forecasts by 1.32%, growing 8% year-over-year.
  • Operating income rose 11% to $1.31B; company maintains strong balance sheet with $13B in cash and investments.
  • New products CASGEVY and JOURNAVX drove growth alongside CF portfolio; executives emphasized continued innovation and market expansion.
  • Company projects Q2 2026 EPS of $4.75 and FY 2026 revenue of $13.02B, though 10 analysts revised earnings downward for upcoming period.
  • Stock rose 0.1% aftermarket to $424.02; VX-522 program discontinued due to patient safety concerns, focus shifting to alternative solutions.
Last Updated: 05/04/2026, 05:59 PM
Read Full Transcript
Vertex investor slides for Q1/2026
Vertex Q1 2026 slides
Last Update: May 04, 2026
See full investor slides

Earnings

Latest Release
May 04, 2026
EPS / Forecast
4.47 / 4.33
Revenue / Forecast
2.99B / 3.03B
EPS Revisions
Last 90 days

VRTX Income Statement

Compare VRTX to Peers and Sector

Metrics to compare
VRTX
Peers
Sector
Relationship
P/E Ratio
25.4x22.1x−0.5x
PEG Ratio
0.050.010.00
Price / Book
5.7x4.6x2.6x
Price / LTM Sales
9.0x2.7x3.1x
Upside (Analyst Target)
28.9%0.0%53.0%
Fair Value Upside
Unlock9.2%6.3%Unlock

Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain. It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of SCD and TDT; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease, which is in single Phase 2 trial; VX-264 for treating Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. The company sells its products primarily to specialty pharmacy and distributors, wholesalers, retail pharmacies, hospitals, and clinics. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

Employees
6400

Ownership

Ownership Overview

Type
Common Stock Held% of Shares OutstandingMarket Value
Mutual Funds & ETFs
156.50M61.66%67.85B
Other Institutional Investors
84.04M33.11%36.43B
Public Companies & Retail Investors
13.26M5.23%5.75B
Total
253.81M100.00%110.03B

Top Holders

Holder
% of holding
Shares Held
Date Reported
Value (In 1,000s)
Capital Research and Management Company18.93%48,053,54920,833,136
The Vanguard Group, Inc.9.50%24,105,82310,450,839

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FAQ

What Is the Vertex (VRTX) Stock Price Today?

The Vertex stock price today is 434.64 USD.

What Stock Exchange Does Vertex Trade On?

Vertex is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Vertex?

The stock symbol for Vertex is "VRTX."

What Is the Vertex Market Cap?

As of today, Vertex market cap is 110.20B USD.

What Is Vertex's Earnings Per Share (TTM)?

The Vertex EPS (TTM) is 16.86.

When Is the Next Vertex Earnings Date?

Vertex will release its next earnings report on Jul 30, 2026.

From a Technical Analysis Perspective, Is VRTX a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Sell.

How Many Times Has Vertex Stock Split?

Vertex has split 1 times.

How Many Employees Does Vertex Have?

Vertex has 6400 employees.

What is the current trading status of Vertex (VRTX)?

As of May 22, 2026, Vertex (VRTX) is trading at a price of 434.64 USD, with a previous close of 433.54 USD. The stock has fluctuated within a day range of 433.39 USD to 438.84 USD, while its 52-week range spans from 362.50 USD to 507.92 USD.

What Is Vertex (VRTX) Price Target According to Analysts?

The average 12-month price target for Vertex is 548.10 USD, with a high estimate of 641 USD and a low estimate of 330 USD. 27 analysts recommend buying the stock, while 1 suggest selling, leading to an overall rating of Buy. The stock has an +26.11% Upside potential.

What Is the VRTX Premarket Price?

VRTX's last pre-market stock price is 433.85 USD. The pre-market share volume is 750.00, and the stock has decreased by 0.31, or 0.07%.

What Is the VRTX After Hours Price?

VRTX's last after hours stock price is 433.95 USD, the stock has decreased by 0.41, or 0.09%.
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