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Chardan bullish on CervoMed, sets $55 stock target on DLB drug potential

EditorIsmeta Mujdragic
Published 09/18/2024, 01:27 PM
CRVO
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On Wednesday, Chardan Capital Markets initiated coverage on NASDAQ:CRVO, CervoMed, with a positive outlook, assigning the stock a Buy rating and a price target of $55. The optimism stems from the potential of CervoMed's leading drug candidate, neflamapimod, which is aimed at treating Dementia with Lewy Bodies (DLB). Chardan's stance is influenced by the drug's mechanism of action and the data supporting its development.

CervoMed emerged from the reverse-merger between EIP Pharma and Diffusion Pharmaceuticals (NASDAQ:CRVO) in August 2023, now concentrating on the progression of neflamapimod for DLB. This particular form of dementia affects approximately 1.4 million individuals in the U.S. and currently lacks approved disease-modifying treatments.

Neflamapimod, which was acquired by EIP Pharma from Vertex Pharmaceuticals (NASDAQ:VRTX) in 2014, is an orally taken, brain-penetrant selective small-molecule inhibitor targeting p38 MAP kinase alpha, a key player in cellular stress pathways, including those resulting from neuroinflammation.

The clinical and preclinical evidence available supports the continued development of neflamapimod with a focus on DLB. Chardan's analysis suggests that the drug has the potential to be a disease-modifying treatment, which could meet the significant unmet medical needs of patients with DLB. Additionally, there is potential for neflamapimod to be used in treating other neurodegenerative conditions.

CervoMed is on track to release topline results from the Phase 2b trial of neflamapimod in patients with early-stage DLB in December 2024. Following the outcomes of this trial, the management of CervoMed is expected to guide the future development plans for neflamapimod, which may include exploring its use in other indications such as Alzheimer's disease, recovery after ischemic stroke, and frontotemporal dementia.

In other recent news, the ongoing RewinD-LB Phase 2b study, funded by a $21.0 million grant from the National Institute on Aging, is evaluating neflamapimod in up to 160 patients with mild DLB, with topline results expected in December 2024.

In addition to these developments, CervoMed has received an Overweight rating from Morgan Stanley, based on the company's development of neflamapimod. The firm sees strong potential for the drug to reverse disease progression and restore function in patients with DLB.

In parallel, Jones Trading has initiated coverage on CervoMed with a Buy rating, indicating that the company's targeted approach could yield probability-adjusted peak sales of approximately $1 billion by 2038.

In other company news, CervoMed has announced the appointment of William Elder as Chief Financial Officer, effective June 1, 2024. Elder, currently serving as General Counsel and Corporate Secretary for the company, brings a combination of biopharmaceutical and financial expertise to his new role.


InvestingPro Insights


As CervoMed (NASDAQ:CRVO) garners attention with its innovative drug candidate neflamapimod, investors are closely monitoring the company's financial health and market performance. According to InvestingPro, CervoMed holds more cash than debt on its balance sheet, which is a positive sign for the company's financial stability. This is particularly relevant as the company progresses through costly clinical trials for neflamapimod.

On the flip side, it's worth noting that analysts expect a decrease in net income this year, and they do not anticipate the company will be profitable within the same timeframe. These InvestingPro Tips highlight the importance of considering both the potential of CervoMed's drug candidate and the financial realities the company faces. For those looking to delve deeper into CervoMed's financial metrics and analyst forecasts, InvestingPro offers additional tips at: https://www.investing.com/pro/CRVO.

InvestingPro Data reveals a market capitalization of $135.79 million for CervoMed, which may reflect investor confidence in the company's growth potential. The company's Price to Book ratio as of the last twelve months stands at 2.72, suggesting that the stock may be valued reasonably in relation to its net assets. Furthermore, the company's revenue growth is impressive, with an increase of 91.23% in the last quarter, indicating potential scalability of their operations as they focus on neflamapimod's development.

With these insights, stakeholders can better gauge the risks and opportunities associated with investing in CervoMed as it navigates the complex landscape of drug development and seeks to make a significant impact on the treatment of Dementia with Lewy Bodies.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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