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IntelGenx launches mid-stage study of Montelukast in Alzheimer's

Published 01/24/2018, 08:46 AM
© Reuters.  IntelGenx launches mid-stage study of Montelukast in Alzheimer's
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  • IntelGenx (OTCQX:IGXT) initiates a Canada-based Phase 2a proof-of-concept study evaluating Montelukast VersaFilm in Alzheimer's disease (AD) patients. The 70-subject trial will enroll patients with mild-to-moderate AD who will receive a once-daily dose for 26 weeks. Screening will commence in March.
  • The tablet formulation of Montelukast has been commercially available in the U.S. since 1997 for the treatment of asthma and allergic rhinitis. The company says an oral film-based formulation offers many advantages over tablets, including the avoidance/minimization of first-pass effects (the concentration of the drug is greatly reduced before it reaches systemic circulation), ease of administration, improved bioavailability, lower dosing and toxicity, better acceptability and improved compliance.
  • Now read: Customers Still Ain't Buying Forrester's 'Age Of The Customer'


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