- An early-stage trial combining drugs from Bristol-Myers (NYSE:BMY) and Innate Pharma (OTC:INNTY, OTCPK:INNMF), showed promise in treating patients with advanced head and neck cancer.
- A trial looked at 29 patients whose cancer had returned after previous treatment, and also at a 17-person subset whose tumors have a marker that’s thought to predict response to Bristol-Myers’s drug, Opdivo. Innate’s drug is known as lirilumab; both are designed to help the immune system attack tumors.
- In the 17 patients in whom at least 1% of their cancer cells expressed the PD-L1 biomarker, 41% had their tumors shrink. Among the wider group, 24% of patients saw their tumors shrink.
- An earlier study of Opdivo alone in a similar group of patients showed that 13% of people with advanced head and neck cancer saw their tumors shrink.
- On Thursday, the FDA approved Opdivo for the treatment of recurrent or metastatic squamous cell head and neck cancer in patients who had been treated previously with chemotherapy.
- Source: press release
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Bristol-Myers cancer drug combo shows promise
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