💎 Fed’s first rate cut since 2020 set to trigger market. Find undervalued gems with Fair ValueSee Undervalued Stocks

Aptevo to launch mid-stage study of otlertuzumab in PTCL this quarter; shares ahead 1%

Published 11/28/2017, 11:42 AM
© Reuters.  Aptevo to launch mid-stage study of otlertuzumab in PTCL this quarter; shares ahead 1%
APVO
-
  • Aptevo Therapeutics (APVO +1%) will launch an open-label proof-of-concept Phase 2 clinical trial this quarter evaluating monospecific antibody candidate otlertuzumab, combined with the chemo agent bendamustine, for the treatment of peripheral T-cell lymphoma (PTCL), a new indication. The primary endpoint of the 24-subject study will be response rate.
  • Enrollment of patients with chronic lymphocytic leukemia (CLL) will be discontinued but the company says it will explore partnerships to support Phase 3 development in CLL.
  • Otlertuzumab targets a B-cell surface protein called CD37 which is also present on the surface of T-cell lymphomas.
  • Aptevo expects to file INDs in 2018 for two bispecific antibody candidates developed with its ADAPTIR platform: APVO436 for acute myeloid leukemia and APVO210 for autoimmune and inflammatory diseases.
  • Now read: Acadia Pharmaceuticals: The Harmony Trial And Buyout Potential


Original article

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers.
© 2007-2024 - Fusion Media Limited. All Rights Reserved.