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Viracta Therapeutics cuts workforce to focus on cancer program

Published 11/06/2024, 05:00 PM
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SAN DIEGO - Viracta Therapeutics, Inc. (NASDAQ: VIRX), a company specializing in precision oncology treatments, announced a strategic reprioritization to concentrate on its Nana-val development program for relapsed or refractory EBV-positive peripheral T-cell lymphoma (PTCL). As part of this refocusing, the company has reduced its workforce by approximately 42%. This reduction is expected to incur around $0.7 million in severance costs.

The company's President and CEO, Mark Rothera, expressed that the decision, while difficult, is aimed at advancing the Nana-val program more efficiently towards a potential New Drug Application submission for its lead indication. Rothera acknowledged the significant contributions of the affected employees and thanked them for their dedication.

Additionally, Viracta has resized its Board of Directors from ten to six members following voluntary resignations effective October 31, 2024. This decision was made to streamline operations and reduce costs, aligning the board size with other similarly sized companies. The remaining board now includes Roger J. Pomerantz, M.D. as Chairman, Flavia Borellini, Ph.D., Thomas E. Darcy, CPA, Mark Rothera, Ivor Royston, M.D., and Barry J. Simon, M.D. Pomerantz recognized the contributions of the departing directors and emphasized the continued focus on the Nana-val program.

Viracta's lead product candidate, Nana-val, is an all-oral combination therapy currently undergoing multiple clinical trials. These include a potentially registrational Phase 2 basket trial for various subtypes of EBV-positive lymphoma and a Phase 1b/2 trial for recurrent or metastatic EBV-positive nasopharyngeal carcinoma and other advanced solid tumors.

The company's strategy is based on its proprietary "Kick and Kill" approach to treating virus-associated cancers. Despite the restructuring, Viracta maintains its commitment to advancing its clinical programs and managing resources to extend its cash runway into 2025.

The information in this article is based on a press release statement from Viracta Therapeutics, Inc.

In other recent news, Viracta Therapeutics has made significant strides in the development of its drug Nana-val for EBV-positive Peripheral T-Cell Lymphoma (PTCL) treatment. The company reported promising results from its NAVAL-1 trial stages 1 and 2, showing substantial antitumor activity. Viracta plans to initiate a Randomized Controlled Trial in 2025, aiming to support a potential New Drug Application filing in 2026.

In a strategic shift, Viracta has decided to halt its solid tumor program to prioritize treatments for EBV-positive lymphoma, resulting in a workforce reduction of approximately 23%. Following these developments, RBC Capital revised its price target for Viracta, while maintaining an Outperform rating on the stock.

Additionally, Viracta appointed Michael Faerm as its new Chief Financial Officer, bringing over 25 years of experience in the life sciences sector. On the financial front, the firm's cash reserves stood at around $30 million as of the second quarter of 2024. These are among the recent developments shaping the future of Viracta Therapeutics.

InvestingPro Insights

Viracta Therapeutics' recent strategic reprioritization aligns with several key financial indicators highlighted by InvestingPro. The company's decision to focus on its Nana-val development program and reduce its workforce comes at a time when it's facing significant financial challenges.

According to InvestingPro data, Viracta's market capitalization stands at a modest $7.58 million, reflecting the company's current struggles. The stock has experienced a substantial decline, with a one-year price total return of -70.65% as of the latest data. This downward trend is further emphasized by the stock trading at just 14.54% of its 52-week high.

InvestingPro Tips reveal that Viracta is "quickly burning through cash" and "suffers from weak gross profit margins." These factors likely contributed to the company's decision to streamline operations and reduce costs. The workforce reduction and board resizing are clear attempts to extend the company's cash runway, as mentioned in the article.

Despite these challenges, it's worth noting that Viracta "holds more cash than debt on its balance sheet," which could provide some financial flexibility as it focuses on advancing its lead product candidate, Nana-val.

For investors seeking a more comprehensive analysis, InvestingPro offers 12 additional tips for Viracta Therapeutics, providing a deeper understanding of the company's financial position and market performance.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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