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UBS highlights asymmetrical risk for Novo Nordisk stock with pivotal obesity trial

EditorEmilio Ghigini
Published 10/03/2024, 03:11 AM
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On Thursday, UBS reiterated its Neutral stance on Novo Nordisk (NOVOB:DC) (NYSE: NYSE:NVO) stock, maintaining the price target of DKK1,100.00.

The firm's focus is on the forthcoming fourth quarter 2024 results from the Phase 3 trials of CagriSema in obesity, which are anticipated to be a significant event for the company. The analysis projects a 70% probability of a positive outcome, which is factored into their base case scenario.

According to UBS, a favorable result that aligns with expectations could lead to a modest 2% increase in Novo Nordisk's net present value (NPV), reflecting a de-risking of the investment. Conversely, outcomes that exceed expectations might result in an 8% rise in NPV. However, should the results disappoint, there is a potential for greater than a 9% decline in NPV.

The firm highlighted the substantial impact that the obesity treatment franchise has on Novo Nordisk's valuation. Given the high expectations set on the CagriSema trial results, a negative outcome could pose asymmetrical downside risks.

UBS anticipates that the share price could experience a double-digit percentage move based on the results of the trial, as stocks tend to react two to three times the NPV impact following clinical trial outcomes.

The market is looking ahead to the fourth quarter of 2024, when Novo Nordisk is expected to release these pivotal results. The outcome will be a defining moment for the company, as it could significantly influence the company's valuation and the future of its obesity franchise. UBS's current rating and price target reflect a cautious optimism balanced with an awareness of the potential risks associated with the trial results.

In other recent news, Novo Nordisk has experienced a series of significant developments. BofA Securities has revised the price target for the company's shares to DKK1,075.00, while maintaining a Buy rating.

This comes in response to disappointing data from the CB1 receptor antagonist trials and muted trends in total prescriptions for the company's drugs Ozempic and Wegovy. The firm also highlighted the importance of the upcoming Phase III data for CagriSema, expected in the fourth quarter of 2024.

Furthermore, Novo Nordisk has implemented strategies to mitigate the impact of ongoing U.S. port strikes, resorting to air freight for shipping its products. Berenberg has maintained its Hold rating on Novo Nordisk amid concerns over the Phase 3 trial results for CagriSema.

Novo Nordisk CEO Lars Jorgensen recently testified before the U.S. Senate Committee on Health, Education, Labor, and Pensions regarding the pricing of Wegovy and Ozempic. BMO Capital Markets maintained an Outperform rating on Novo Nordisk, despite mixed results from the phase 2a trial of Monlunabant, a weight loss drug.

Lastly, a lawsuit against the U.S. law mandating drug price negotiations for Medicare was revived by the 5th U.S. Circuit Court of Appeals, potentially impacting Novo Nordisk as its diabetes medication, Ozempic, is under scrutiny for potential inclusion in the 2027 Medicare price negotiations.

InvestingPro Insights

Novo Nordisk's financial metrics and market performance offer additional context to UBS's analysis. The company's revenue growth of 28.15% over the last twelve months and a strong EBITDA growth of 36.32% underscore its robust performance in the pharmaceutical sector. This aligns with UBS's focus on the potential impact of the CagriSema trial results, as positive outcomes could further boost these already impressive growth figures.

InvestingPro Tips highlight Novo Nordisk's position as a "Prominent player in the Pharmaceuticals industry" and note that it has been "Profitable over the last twelve months." These factors support the significance of the upcoming trial results and their potential to influence the company's market position.

However, investors should note that Novo Nordisk is "Trading at a high earnings multiple" with a P/E ratio of 38.97, suggesting that positive expectations may already be priced into the stock. This high valuation could explain UBS's cautious Neutral stance and underscores the potential for volatility following the trial results.

For readers interested in a deeper analysis, InvestingPro offers 9 additional tips for Novo Nordisk, providing a more comprehensive view of the company's financial health and market position.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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