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Tempus and BioNTech team up to advance cancer therapies

Published 09/04/2024, 08:46 AM
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CHICAGO - Tempus AI, Inc. (NASDAQ: TEM), a leader in artificial intelligence-powered precision medicine, has entered into a multi-year collaboration with BioNTech SE (Nasdaq: NASDAQ:BNTX), an immunotherapy company known for pioneering novel therapies for cancer and serious diseases. The partnership aims to utilize Tempus' vast multimodal datasets to bolster BioNTech's oncology pipeline.

The strategic alliance will see Tempus provide BioNTech with analytical and computational biology support to enhance the research and development of new cancer treatments. BioNTech plans to harness Tempus' real-world multimodal database to uncover insights into the biological mechanisms that underpin the discovery of novel therapies and support the development of their clinical oncology pipeline.

Ryan Fukushima, Chief Operating Officer of Tempus, expressed optimism about the partnership's potential to impact cancer care. "By applying Tempus' extensive real-world multimodal data to BioNTech's AI capabilities and multi-platform discovery engine, we believe we can generate a real impact by working to bring novel therapies to those cancer patients who could potentially benefit the most," he said.

Tempus, renowned for its significant libraries of multimodal data and an operating system designed to make this data accessible and useful, provides AI-enabled precision medicine solutions. Their technology is used by physicians for personalized patient care and supports the discovery, development, and delivery of optimal therapeutics.

The press release contains forward-looking statements regarding the anticipated outcomes and benefits of the collaboration. However, these statements are subject to various risks and uncertainties and should not be relied upon as guarantees of future performance. Tempus has clarified that these forward-looking statements are based on current expectations and projections, which are subject to change.

This collaboration represents a significant step in the application of AI and real-world data in the pursuit of advancing cancer treatment options. The information for this article is based on a press release statement.

In other recent news, Pfizer (NYSE:PFE) and BioNTech have received approval from the FDA for their updated COVID-19 vaccine, adapted for the Omicron KP.2 variant. This comes in line with the FDA's recommendation for the 2024-2025 fall and winter season, expecting KP.2 to be the prevalent strain. The vaccine has shown a significantly improved response against currently circulating Omicron sublineages, including KP.2, KP.3, and LB.1.

BioNTech reported a widening net loss in the second quarter due to a 23% decline in revenue, largely due to reduced sales of its COVID-19 vaccine. Despite this, H.C. Wainwright and HSBC maintained their Buy ratings, while TD Cowen, Morgan Stanley, and BMO Capital adjusted their price targets due to the company's financial performance and increased operational expenses.

BioNTech and Pfizer revealed partial trial results for their combination influenza-COVID-19 vaccine. The vaccine met one of the two primary immunogenicity goals in a Phase 3 trial. The companies are now considering modifications to enhance the vaccine's efficacy against influenza B.

BioNTech is shifting its focus towards its oncology pipeline, with several key updates expected in the near future. These updates include Phase 1/2 data for BNT113 in HPV16-induced carcinomas, BNT327 in renal cell carcinoma, and BNT211 in CLDN6-positive tumors. Additionally, BioNTech and DualityBio received Fast Track designation from the FDA for their investigational drug, BNT324/DB-1311, for treating patients with metastatic castration-resistant prostate cancer. These are recent developments that highlight BioNTech's active approach to drug development.

InvestingPro Insights

As BioNTech SE (Nasdaq: BNTX) embarks on this promising collaboration with Tempus AI, Inc., it's valuable to consider some key financial metrics and insights that could provide a backdrop to this strategic partnership. BioNTech's commitment to innovation in oncology is mirrored in its financial positioning and management strategies.

InvestingPro data highlights that BioNTech holds a market capitalization of $20.92 billion, reflecting a significant presence in the biotechnology market. Despite a challenging period with revenue growth declining by 70.7% over the last twelve months as of Q2 2024, the company's gross profit margin remains strong at 82.91%. This suggests that while BioNTech's sales may have faced headwinds, the company retains a robust ability to control costs and maintain profitability on its products.

In terms of InvestingPro Tips, it's notable that BioNTech management has been actively buying back shares, which can be a sign of confidence in the company's future prospects. Additionally, BioNTech holds more cash than debt on its balance sheet, indicating a solid financial position that could support ongoing research and development efforts, such as the collaboration with Tempus.

While analysts have revised their earnings downwards for the upcoming period and anticipate a sales decline in the current year, BioNTech's valuation implies a strong free cash flow yield. This could be an attractive point for investors looking for companies with the potential to generate cash post-investment.

For readers interested in a deeper dive into BioNTech's financials and future outlook, there are additional InvestingPro Tips available at https://www.investing.com/pro/BNTX, providing a more comprehensive analysis of the company's performance and projections.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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