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Piper Sandler starts Abivax stock with Overweight, optimistic on obefazimod's market potential

EditorEmilio Ghigini
Published 04/29/2024, 04:20 AM
ABVX
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On Monday, Piper Sandler initiated coverage on Abivax (NASDAQ:ABVX) stock, a biopharmaceutical company, bestowing an Overweight rating and setting a price target of $42.00.

The firm's optimism is anchored in the potential of Abivax's lead drug candidate, obefazimod, which is being developed for the treatment of inflammatory bowel disease (IBD).

The firm's analyst highlighted the drug's promising Phase 2 ulcerative colitis (UC) data, citing its JAK-like efficacy during induction treatment without the safety concerns typically associated with JAK inhibitors. Obefazimod's mechanism of action is seen as differentiated, offering competitive efficacy and superior safety, potentially positioning it as a category leader in IBD treatments.

According to Piper Sandler, obefazimod not only matches the efficacy of current treatments but also demonstrates superior durability compared to the dominant modes of action in the market, which include JAK inhibitors, TNF blockers, and IL-23 inhibitors. This durability is a significant factor in the firm's positive assessment.

The firm anticipates increased visibility for Abivax as the company progresses through its clinical trials. Phase 3 data for ulcerative colitis is expected in the first quarter of 2025, and Phase 2 data for Crohn's disease is likely to follow approximately a year later. These milestones are key in the firm's evaluation of the company's prospects.

The price target of $42.00 is based on a valuation model that applies an 8X multiple to the firm's 2033 revenue estimate for obefazimod, which is approximately €1.29 billion, or around $1.37 billion. This figure is then discounted back at a rate of 20% per year. Piper Sandler's coverage initiation reflects a strong conviction in Abivax's pipeline and its future in the IBD market.

InvestingPro Insights

As Abivax garners attention with its promising drug candidate obefazimod, real-time data and InvestingPro Tips can provide a more nuanced view of the company's financial health and market performance. Abivax's market capitalization stands at approximately $999.2 million, indicating a significant presence in the biopharmaceutical sector. Despite its potential, analysts are cautious, expecting a sales decline in the current year and not anticipating profitability for the company within this timeframe. This aligns with the company's current P/E ratio of -4.02 and an adjusted P/E ratio for the last twelve months as of Q4 2023 at -6.2, reflecting investor skepticism about near-term earnings.

However, Abivax's strong return over the last three months, with a 19.0% price total return, and a substantial 70.04% increase over the last six months, demonstrates market optimism regarding the company's long-term prospects. This recent price performance is supported by the fact that Abivax holds more cash than debt on its balance sheet and has liquid assets that exceed its short-term obligations, providing a degree of financial stability.

For investors seeking a deeper dive into Abivax's financials and future outlook, there are additional InvestingPro Tips available. These can be accessed by visiting the InvestingPro platform for ABVX at https://www.investing.com/pro/ABVX. To enrich your investment strategy, use coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription. Note that there are 6 more InvestingPro Tips available that could further inform your investment decisions in Abivax.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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