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NovoCure shares target raised on METIS trial optimism

EditorAhmed Abdulazez Abdulkadir
Published 03/27/2024, 12:25 PM
NVCR
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On Wednesday, H.C. Wainwright adjusted the price target for NovoCure Ltd. (NASDAQ:NVCR) to $24.00 from the previous $22.00, while maintaining a Neutral rating on the stock. The adjustment follows the recent positive topline results from the METIS trial, which investigated the effectiveness of NovoCure's treatment for brain metastases from non-small cell lung cancer (NSCLC).

The firm's analyst updated their model to reflect an increased probability of success (POS) for the treatment, raising it to 80% from the prior 60%. The optimism is based on the significant extension of intracranial time to progression and the absence of additional safety risks compared to stereotactic radiosurgery (SRS) alone. The analyst expects that these factors contribute to a high likelihood of approval for NovoCure's treatment in this indication.

The forecast for NovoCure includes a peak market share of 15% and anticipates a product launch in 2026, assuming that the company will submit its application to the FDA by early 2025. The projected peak sales for the treatment reach $1.1 billion by 2037. The market opportunity is considered substantial, as approximately 25% of NSCLC patients develop brain metastases, with up to half experiencing brain metastases at some point during their illness.

The analyst also notes the potential synergy between the treatment for brain metastases from NSCLC and NovoCure's existing glioblastoma multiforme (GBM) business, as well as an anticipated second-line metastatic NSCLC treatment launch in 2025. In preparation for the launch, the analyst expects NovoCure to increase investments in their sales force focused on NSCLC, leading to higher selling, general, and administrative (SG&A) expenses for 2024.

These updated estimates and market opportunities are the driving factors behind the increase in NovoCure's price target to $24.00.

InvestingPro Insights

As NovoCure Ltd. (NASDAQ:NVCR) navigates the path towards FDA approval for its NSCLC treatment, investors and analysts are closely monitoring the company's financial health and market performance. According to real-time data from InvestingPro, NovoCure holds a market capitalization of $1.61 billion, with a notable gross profit margin of approximately 74.96% over the last twelve months as of Q4 2023. Despite the company's impressive gross profit margins, it is important to note that NovoCure has not been profitable over the same period, with an operating income margin of -44.4%.

InvestingPro Tips highlight a couple of key aspects that investors should consider. NovoCure's balance sheet reflects a positive position, holding more cash than debt, which is a reassuring sign of financial stability. Additionally, three analysts have revised their earnings upwards for the upcoming period, indicating a potential shift in market sentiment. However, it's worth mentioning that the stock has experienced significant price volatility and has underperformed over the last month, with a 19.82% decline.

For investors seeking more comprehensive analysis, InvestingPro provides additional tips on NovoCure, which can be accessed at https://www.investing.com/pro/NVCR. To delve deeper into the company's prospects and gain further insights, consider using the coupon code PRONEWS24 for an additional 10% off a yearly or biyearly Pro and Pro+ subscription. With this subscription, you'll find an array of InvestingPro Tips that could help inform your investment decisions regarding NovoCure.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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