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MediciNova secures patent for ARDS treatment

EditorAhmed Abdulazez Abdulkadir
Published 05/14/2024, 06:29 AM
MNOV
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LA JOLLA, Calif. - MediciNova, Inc., a biopharmaceutical company listed on NASDAQ:MNOV and the Tokyo Stock Exchange (Code Number: 4875), announced today that it has received a Notice of Allowance for a patent covering its drug MN-166 (ibudilast) for treating chlorine-induced acute respiratory distress syndrome (ARDS).

The U.S. Patent and Trademark Office's approval signifies the company's intellectual property rights for the use of MN-166 as a monotherapy or in combination with other drugs through various administration methods, including oral, intravenous, subcutaneous, intramuscular, and inhalation, with a wide range of dosages and treatment periods.

This patent, once issued, is expected to provide exclusivity until at least January 2042. Dr. Kazuko Matsuda, Chief Medical Officer at MediciNova, expressed optimism about the patent allowance, noting the demonstrated efficacy of MN-166 in nonclinical model studies, where it showed significant improvement in pulmonary function and survival rates.

MN-166 is a small molecule compound that inhibits phosphodiesterase type-4 (PDE4) and certain inflammatory cytokines. It is currently in late-stage clinical development for various neurodegenerative diseases, including ALS, progressive MS, and degenerative cervical myelopathy. The drug is also under evaluation for other conditions such as glioblastoma, Long COVID, chemotherapy-induced peripheral neuropathy, and substance use disorder.

MediciNova's pipeline is based on two compounds, MN-166 and MN-001 (tipelukast), which are being developed for inflammatory, fibrotic, and neurodegenerative diseases. The company has a history of securing government grants for investigator-sponsored clinical trials.

InvestingPro Insights

As MediciNova, Inc. continues to advance its clinical development and secure intellectual property rights for its drug candidates, investors are closely monitoring the company's financial health and market potential. Real-time data from InvestingPro provides valuable insights into the company's current financial status and future prospects.

With a market capitalization of $74.55 million, MediciNova appears to be a smaller player in the biopharmaceutical industry. The company's Price to Earnings (P/E) ratio stands at -8.95, reflecting that it is not currently generating a profit. This is further supported by the adjusted P/E ratio for the last twelve months as of Q1 2024, which is -8.87. Additionally, the company holds a Price to Book (P/B) ratio of 1.25, suggesting that its market value is somewhat in line with its book value.

Despite the challenges, InvestingPro Tips highlight some positive aspects for MediciNova. The company holds more cash than debt on its balance sheet, which is a sign of financial stability. Furthermore, its liquid assets exceed short-term obligations, indicating good liquidity. Analysts anticipate sales growth in the current year, which could be a positive signal for future revenue streams. On the performance front, MediciNova has seen a significant return over the last week with a 14.29% price total return.

Investors interested in a deeper analysis can find additional InvestingPro Tips for MediciNova. These tips cover a range of metrics, including anticipated net income changes and profitability expectations. To access these insights and more, visit https://www.investing.com/pro/MNOV and consider using the coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription. There are currently 4 additional InvestingPro Tips listed for MediciNova that could provide further guidance for those considering an investment in the company.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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