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FDA approves burn treatment NexoBrid for pediatric use

Published 08/15/2024, 04:10 PM
VCEL
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CAMBRIDGE, Mass. - Vericel (NASDAQ:VCEL) Corporation (NASDAQ:VCEL), a biopharmaceutical company specializing in advanced therapies, announced that the U.S. Food and Drug Administration (FDA) has approved the use of NexoBrid for pediatric patients. This biologic product, which contains proteolytic enzymes, is designed for eschar removal in children with deep partial-thickness and/or full-thickness thermal burns.

The FDA's approval is rooted in the outcomes of the global Phase 3 clinical trial, Children Innovation Debridement Study (CIDS), as well as additional pediatric data from other clinical studies. The decision enables the expansion of NexoBrid's target market to include around 20 pediatric burn centers across the United States.

NexoBrid offers a non-surgical alternative to traditional burn care methods, which may be particularly beneficial for pediatric patients. According to Dr. Steven Kahn, Chief of Burn Surgery at MUSC, University Hospital and Shawn Jenkins Children’s Hospital, this approval provides children access to "a less invasive alternative" for effective burn treatment.

Previously, NexoBrid had been approved for adult use by the FDA on December 28, 2022, and is currently available commercially in the U.S. Vericel expects that the pediatric indication will significantly contribute to the product's adoption over time.

Despite the enthusiasm for NexoBrid's expanded indication, it is important to note the limitations of use. The product is not recommended for chemical or electrical burns, burns on sensitive areas such as the face, perineum, or genitalia, or for patients with certain medical conditions, including significant cardiopulmonary disease or coagulation disorders.

The most common adverse reactions observed in adults and pediatric patients include pruritus, pyrexia, and vomiting. Healthcare professionals are advised to take precautions to avoid exposure when preparing and handling NexoBrid.

Vericel's portfolio also includes MACI, for cartilage defects of the knee, and Epicel, a permanent skin replacement for deep dermal or full-thickness burns. This news is based on a press release statement from Vericel Corporation.

In other recent news, Vericel Corporation has been experiencing significant developments. Canaccord Genuity recently initiated coverage on Vericel, assigning a Buy rating and setting a price target of $57.00. The firm's analysis points to Vericel's diverse biomaterial product portfolio and a compound annual growth rate (CAGR) of 20% in revenue, predicting continued robust growth for the company. Canaccord Genuity also anticipates a profitability inflection point for Vericel, leading to future cash flow generation.

In addition to the analyst coverage, Vericel posted robust financial results for the second quarter of 2024, achieving a record revenue of nearly $53 million. This strong performance was driven by the growth in their MACI product and solid demand for NexoBrid. The company also raised its profitability outlook for the year and is preparing to launch MACI Arthro, further contributing to its growth.

These recent developments underscore the ongoing momentum at Vericel Corporation. As the company continues to innovate and expand within its market segments, analysts and investors alike will be closely watching its progress.

InvestingPro Insights

Vericel Corporation (NASDAQ:VCEL) has shown a remarkable capacity for growth, with a revenue increase of 20.39% over the last twelve months as of Q2 2024. This financial trajectory is particularly noteworthy as the company navigates the biopharmaceutical market, focusing on advanced therapies like NexoBrid. With a market capitalization of $2.26 billion, Vericel is demonstrating its potential within the competitive landscape of biotech firms.

One of the key metrics for investors to consider is the company's P/E ratio, which currently stands at a high 2895.83, reflecting a significant earnings multiple. This could indicate investor confidence in Vericel's future profitability, especially considering that analysts predict the company will be profitable this year. This optimism is supported by a robust gross profit margin of 70.42%, underscoring the company's efficiency in generating profit from its revenues.

From an investment standpoint, Vericel's stock price movements have been quite volatile, which might appeal to certain investors looking for dynamic trading opportunities. However, it's essential to note that Vericel does not pay a dividend to shareholders, which could influence the investment decisions of those seeking regular income streams from their investments.

For those who are considering adding VCEL to their portfolio, there are additional InvestingPro Tips available that provide deeper insights into the company's financial health and market position. With a total of 12 tips listed on InvestingPro, including observations about the company's moderate level of debt and liquid assets that exceed short-term obligations, investors can gain a comprehensive understanding of Vericel's financial landscape.

For further details and investment advice, potential investors can explore more tips on InvestingPro, which offers a wealth of information to guide investment decisions in the biopharmaceutical sector.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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