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Aligos Therapeutics names new chief medical officer

Published 09/24/2024, 08:09 AM
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SOUTH SAN FRANCISCO - Aligos Therapeutics, Inc. (NASDAQ:ALGS), a biopharmaceutical company focusing on liver and viral diseases, today announced the immediate appointment of Dr. Hardean Achneck as its new Chief Medical Officer (CMO). Dr. Achneck, with a rich background in clinical development, joins Aligos' Senior Leadership Team to propel the company's clinical development programs.

Dr. Achneck's experience spans across hepatology and infectious diseases, areas that align with Aligos' therapeutic focus. His previous roles include Senior Vice President at Pliant Therapeutics (NASDAQ:PLRX) and Vice President of Clinical Development at Dicerna Therapeutics, which was acquired by Novo Nordisk (NYSE:NVO) (NYSE:NVO; Nasdaq:Novo-B) in 2021.

The appointment comes on the heels of Aligos' recent positive topline data for its ALG-055009 treatment in MASH (metabolic dysfunction-associated steatohepatitis) subjects. Dr. Achneck's strategic vision is anticipated to be crucial as the company advances towards later-stage clinical trials with its pipeline of liver and viral therapies.

Dr. Achneck's industry experience is complemented by his academic tenure as an Assistant Professor at Duke University School of Medicine and his involvement with Duke-National University of Singapore. He holds an M.D. from Yale University School of Medicine and has been licensed to practice medicine in the U.S. and EU.

Aligos Therapeutics, with its mission to develop best-in-class therapies, has been advancing a purpose-built pipeline addressing metabolic dysfunction-associated steatohepatitis (MASH) and other diseases with high unmet medical needs, including hepatitis B and coronaviruses.

The company's forward-looking statements indicate ongoing research and development activities and potential future announcements related to regulatory filings and clinical trials. These statements also acknowledge the inherent risks and uncertainties in drug development and the need for sufficient capital resources to fund operations.

This announcement is based on a press release statement from Aligos Therapeutics.


In other recent news, Aligos Therapeutics has made significant strides in its various programs. The company has reported positive results from its Phase 2a HERALD study on ALG-055009, a drug intended for the treatment of metabolic-dysfunction associated steatohepatitis (MASH). The study demonstrated significant reductions in liver fat content after a 12-week treatment period. This development follows the company's successful return to compliance with Nasdaq's minimum bid price requirement, averting the risk of delisting from the exchange.

Aligos Therapeutics has also been the subject of several analyst notes. Piper Sandler reaffirmed its Overweight rating and $175.00 price target for Aligos, emphasizing the potential of its ALG-000184, a candidate for chronic hepatitis B treatment. Similarly, H.C. Wainwright initiated coverage on Aligos Therapeutics with a Buy rating, highlighting the potential of ALG-055009 in a Phase 2a study and ALG-000184 in a Phase 1b trial.

In addition, Aligos reported promising Phase 1 results for its pan-coronavirus protease inhibitor, ALG-097558. The company also received shareholder approval to increase its authorized common stock from 300 million to 500 million shares and made amendments to its 2020 Incentive Award Plan. These are among the recent developments in Aligos Therapeutics' journey.


InvestingPro Insights


As Aligos Therapeutics (NASDAQ:ALGS) welcomes Dr. Hardean Achneck as the new Chief Medical Officer, the company's financial health and stock performance remain critical factors for investors. With a market capitalization of roughly $49.93 million, Aligos is navigating a challenging phase, as evidenced by recent InvestingPro data. The company's stock price has significantly declined over the past week, month, and six months, with a 43.71% drop just in the last week and a 67.27% decrease over the past six months. This volatility is reflected in the stock trading near its 52-week low, with price movements indicating the market's reaction to both company-specific developments and broader sector trends.

An InvestingPro Tip worth noting is that Aligos holds more cash than debt on its balance sheet, which is a positive sign of liquidity. This is especially pertinent given that the company is quickly burning through cash, a situation that investors should monitor closely. As the company focuses on advancing its clinical development programs under Dr. Achneck's leadership, the cash position could be a crucial factor in sustaining operations and research.

Furthermore, the company's revenue has experienced a sharp decline, with a 53.82% decrease over the last twelve months as of Q2 2024. This, combined with weak gross profit margins and analysts' anticipation of a sales decline in the current year, suggests that Aligos faces significant financial headwinds. Despite these challenges, Aligos' liquid assets exceed short-term obligations, providing some financial cushioning.

Investors interested in a deeper dive into Aligos' financials and stock performance can find additional InvestingPro Tips on the company's profile at https://www.investing.com/pro/ALGS. With a total of 14 InvestingPro Tips available, including insights into profitability forecasts and valuation implications, these resources can help investors make more informed decisions regarding Aligos Therapeutics.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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