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Ainos receives IRB nod for HIV-related oral wart trial

Published 09/25/2024, 08:09 AM
AIMD
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SAN DIEGO - Ainos, Inc. (NASDAQ:AIMD)(NASDAQ:AIMDW), a healthcare company specializing in AI-driven point-of-care testing and low-dose interferon therapeutics, has announced the Institutional Review Board (IRB) approval for a clinical trial at the National Taiwan University Hospital. This study will evaluate the efficacy of VELDONA®, the company's oral interferon drug, in treating oral warts in HIV-positive patients.

The IRB approval, granted on September 18, 2024, allows Ainos to proceed with the trial titled "Evaluation of Human Interferon Alpha Administered Oromucosally in the Treatment of Oral Warts in HIV-Seropositive Subjects Receiving Combination Anti-Retroviral Therapy." The study will enroll 40 participants, with a 1:3 random assignment to either the VELDONA® group or a placebo group. The treatment involves taking 10 sublingual tablets daily for 24 weeks, with the primary goal to assess VELDONA®'s efficacy in conjunction with antiretroviral therapy.

VELDONA® has been designated as an orphan drug by the U.S. Food and Drug Administration (FDA), a status that underscores the treatment's potential and provides regulatory benefits to expedite its commercial availability. Oral warts are a prevalent issue among the HIV-positive population, affecting their quality of life. UNAIDS reported approximately 39.9 million people living with HIV worldwide in 2023, with Taiwan accounting for about 35,500 individuals and 666 new cases as of August 2024.

Before the trial's commencement, Ainos must secure approval from the Taiwan Food and Drug Administration (TFDA), having submitted an application on August 28, 2024. The Site Initiation Visit is expected in November 2024, with patient enrollment projected to last a year and study completion by July 2026.

Ainos, headquartered in San Diego, is known for its development of human and animal oral therapeutics, human orphan drugs, and AI-powered point-of-care testing solutions. The company's product pipeline is clinical-stage, and it aims to address unmet medical needs through innovation.

This news is based on a press release statement from Ainos, Inc. The company's forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from those projected. These include the cost and sales potential of their products, market competition, and the company's financial stability and ability to continue product development. Ainos has made no commitment to update any forward-looking statements, and the information presented is as of the current date only.


In other recent news, Ainos Inc., a healthcare company, has announced several significant developments. The company plans to initiate a clinical trial of its VELDONA® formulation, aimed at treating oral warts in HIV-positive patients, at the National Taiwan University Hospital. The study, which will assess the efficacy of VELDONA® in HIV-positive individuals undergoing antiretroviral therapy, is set to commence in November 2024.

Moreover, Ainos has secured a patent in Taiwan for its antiviral drug, VELDONA®, which targets the treatment and prevention of coronavirus infections. The company's AI Nose technology has also achieved a 79% accuracy rate in detecting volatile organic compounds in Japanese semiconductor factories, a development expected to improve safety and efficiency in the industrial sector.

In a strategic move, Ainos has acquired exclusive licenses for 10 invention patents from Taiwan Carbon Nano Technology, valued at approximately $5.4 million. This acquisition is anticipated to enhance the company's AI Nose and point-of-care testing technologies. However, Ainos faces a potential delisting from the Nasdaq due to its stock price falling below the required minimum bid price, with a grace period until January 13, 2025, to regain compliance. These are the recent developments at Ainos, Inc.


InvestingPro Insights


Ainos, Inc. (NASDAQ:AIMD), while taking significant strides in the healthcare sector with its clinical trials, presents a challenging financial landscape according to real-time data from InvestingPro. The company's market capitalization stands at a modest $3.78 million, indicating its small size in the industry. Notably, the company's recent financial performance has been concerning, with a gross profit margin of -316.61% for the last twelve months as of Q2 2024, reflecting substantial costs exceeding revenues. This aligns with one of the InvestingPro Tips, highlighting the company's weak gross profit margins.

The stock price dynamics also tell a cautionary tale, as AIMD has experienced a significant decline over various time frames, including a 24.69% drop over the last month and a staggering 85.72% fall over the last year. This performance is in line with another InvestingPro Tip, noting that the stock has fared poorly over the last month. The current price is hovering near its 52-week low, at only 11.24% of its highest value over the past year, and the InvestingPro fair value estimate stands at $0.55, slightly above the previous close price of $0.48.

For investors seeking a deeper understanding of Ainos, Inc.'s financial health and stock performance, additional InvestingPro Tips are available. Currently, there are 11 more tips listed on InvestingPro that could provide further insights into the company's cash flow, industry positioning, and dividend policies, among other key factors. These tips could be particularly valuable for those considering investment decisions related to Ainos, Inc.

It is essential for investors to consider both the potential of Ainos' clinical developments and its financial metrics to make informed decisions. As the company progresses with its clinical trial for VELDONA®, the InvestingPro platform offers a comprehensive view of the financial aspects that could impact the company's future.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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